Fibrin Microbead – Would It Improve Clinical Application of Stem Cells

June 17, 2009 By Leave a Comment

One of the major difficulty in stem cell linical application is the inability of cellular structures to integrate and survive and repair the damaged target tissues. Injected single cells also survive poorly and can hardly integrate in tissues.

A  practical solution is to deliver the cells on small particulate matrix, in a manner that can allow their integration in the tissues. Fibrin micro-beads  has  higher cell binding capability than native fibrin gel. FMB bind matrix dependent cells and this may be used for the isolation of mesenchymal stem cells. [Read more...]

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What Is A Stem Cell bank

June 13, 2009 By Leave a Comment

A cell bank in its simplest form is a collection of containers of cryopreserved cells that are intgral part of a homogenous cell suspension derived from a single culture of cells.Cells are stored at ultra-low temperature and in this state the cells remain viable indefinitely. On thawing they are able to divide again.

A cryopreserved bank of cells is a kind of freezed culture. The cells can be characterised, qualified
and shared. [Read more...]

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Link Between Stem Cells and Regenerative medicine

June 10, 2009 By Leave a Comment

Regenerative medicine was the term coined by William A. Haseltine in 2000. This  tries to heal the body by stimulation of endogenous cells to repair damaged tissues, or transplantation of cells or engineered tissues to replace diseased or injured.

Tissue injuries are normally repaired by formation of fibrous scar tissue in humans. But a number of tissues in mammals including epithelia, bone marrow, and muscle undergo regeneration to keep tissue integrity after cell loss .

Some lower animals can undertake full organ regeneration.Though not entirely clear, two  mechanisms play roles in regeneration. [Read more...]

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A Protein That Induces Stem Cells Found To Stimulate Muscle Regeneration

June 9, 2009 By Leave a Comment
body_building

body_buildingA protein called Wnt7a has been found to increase the number of stem cells in muscle tissue, leading to accelerated growth and repair of skeletal muscle. This has been found in a study research at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa.

The finding shows that, by targeting stem cells to boost their numbers, we can improve the body’s ability to repair muscle tissue, senior author Dr. Michael Rudnicki was reported saying.

Rudnicki is the scientific director of Canada’s Stem Cell Network and a professor of medicine at the University of Ottawa.

[Read more...]

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International Policy on Human Embryonic Stem Cell Research

June 8, 2009 By Leave a Comment
parliament

parliamentThe policies on human embryonic stem cell   research used by different countries vary tremendously and change frequently. The policies are determined by the government stand religious stand and political awareness etc.

Here is major categorization

Permissive:

This policy allows various embryonic stem cell derivation techniques including somatic cell nuclear transfer (SCNT), also called research or therapeutic cloning. [Read more...]

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Embryonic Stem Cells and Regenerative Medicine

June 5, 2009 By Leave a Comment

Under appropriate culture conditions, embryonic have demonstrated a remarkable ability to self-renew continuously, that is, to produce more cells like themselves that are multipotent.

Human embryonic stem cells that have been propagated for more than two  years also demonstrate a stable and normal complement of chromosomes. This is in contrast to the unstable and abnormal complement of embryonic cancer cell lines used in the past.

Research on human embryonic stem cells is very recent. The data about properties of stem cells comes from mice. [Read more...]

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Hematopoietic Stem Cells – An Alternative?

June 4, 2009 By Leave a Comment

Role of bone marrow transplants in increasing the survival of patients with leukemia and other cancers, inherited blood disorders, and diseases of the immune system and it is an inspiration to stem cell research.

Hematopoietic stem cells are used in bone marrow transplant and have the ability to self renew in the marrow and to differentiate into the full complement of cell types found in blood. [Read more...]

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Stem Cells Creted From Pig Cells In China

June 3, 2009 By Leave a Comment
pig

pigScince Daily had reported via EurekaAlert a research published in journal of molecular cell biology that scientists have managed to induce cells from pigs to transform into pluripotent stem cells. Pluripotent cells aare cells like embryonic stem cells, are capable of developing into any type of cell in the body.

It is a breakthrough. It is the first time in the world that this has been achieved using somatic cells (cells that are not sperm or egg cells) from any animal with hooves or ungulates. [Read more...]

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Controversis Around Embryonic Stem Cell Research – Are Adult Cells An option

June 2, 2009 By Leave a Comment

Adult stem cell is cited as possible and viable alternative when a ban on embryonic stem cell is asked.  It is true that re adult stem cells have the potential and area morally less problematic alternative.

But  there are a  lot of possible  problems. First is that human adult stem cells are rare, of few types  and difficult to isolate.

Most of these are difficult to grow in culture. Much of the work on human adult cells is of hematopoietic stem cells an results of this work can not be generalized to other types.

However, adult stem cells if they can be harnesses have potential to produce  histocompatible transplant which would not trigger immunological responses.

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Controversies Surrounding Embryonic Stem Cell Research

June 1, 2009 By Leave a Comment
Stem cells are surrounded by controversies
Stem cells are surrounded by controversies

Stem cells are surrounded by controversies

Embryonic stem cells have been center of controversies. The issue s involved are legal, ethical, religious and moral. As it involves area surrounding human reproduction, it is natural to get much attention and opinion from all authorities and fields just like contraception, abortion, and in vitro fertilization.

Actually it is the way society takes this issue of human life and the moral and legal status of the human embryo.

Greatest objection to embryonic stem cell research comes from the fact that research deprives a human embryo of any further potential to develop into a complete human being.

It amounts to killing of  life  of  a human being and killing humans for treating humans is not justified. But even society does not universally agrees when an embryo can be called live.

Let us look at this [Read more...]

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