Diabetes Reversal By Stem Cells

Recent developments have suggested that stem cells are able to reverse the diabetes. In near future a cure might be offered for other autoimmune diseases.

Read full article here on how stem cells can reverse the diabetes.

One Year of Not Writing

My last post has been made in December.

That makes it one almost a year of no posting.

I had been occupied. Too much occupied.

I would be regular now.

More on stem cells soon

Stem Cells Found To Protect Tuberculous Bacteria

There are certain stem cells that  protect tuberculosis bacteria from destruction by body  researchers said in a paper published in the Proceedings of the National Academy of Sciences on Monday.

That explains why tuberculous bacteria could lie dormant for decades all together.

What happens is master stem cells, produced by bone marrow make a barrier between the T-cells that are supposed to kill the bacteria, and the bacteria.

Proc Natl Acad Sci. Posted online December 6, 2010.

Evidence Of HIV Cure By Stem Cell Transplantation

In a recently published study in Blood , a strong evidence has been found of HIV cure in a patient who received CCR5 Delta 32/Delta32 stem cells.
This has raised hopes for constructing a permanent cure for HIV through genetically-engineered stem cells.

HIV entry into CD4+ cells requires interaction with a cellular receptor, generally either CCR5 or CXCR4.

Previously, the authors had reported a case of an HIV-infected patient in whom viral replication remained absent despite discontinuation of antiretroviral therapy after transplantation with CCR5{Delta}32/{Delta}32 stem cells.

In the present study, authors have demonstrate successful reconstitution of CD4+ T cells at the systemic level as well as in the gut mucosal immune system following CCR5Delta32/Delta32 stem cell transplantation, while the patient remained asymptomatic.

The results strongly suggest that cure of HIV has been achieved in this patient.

Blood: DOI 10.1182/blood-2010-09-309591.

Cord Blood Cells – Powerful Source of Stem Cells

Cord blood cells were often wasted previously but now they are viewed as a powerful source of stem cells.

This video explains nicely about cord blood cells.

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What Are Stem Cells – The Video Explains Beautifully

This is a nice video that explains what are stem cells and how do they work and develop. I wanted to share it with all of you

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First Stroke Patient Treated With Neural Stem Cell Therapy

It is a coincidence that last post on this blog is a question on use of stem cells in clinical settings.

Almost a year has passed since that post and the site went on to sheer neglect for whatever reasons.

Today I came across a news so exciting, at Medscape that I could not hold myself from posting it. [Read more...]

Clinical Use of Stem Cells – When It Is Going to Happen

Our goal of use of stem cells in clinical practice is far from true. An intensive research is going to realize the promise of novel cell-based therapies. There are few needs that must be fulfilled before stem cells can be used in clinical practice.

we  must be able to manipulate stem cells so that they possess the necessary characteristics for successful differentiation, transplantation, and engraftment.

The following is a list of steps in successful cell-based treatments that scientists will have to learn to control to bring such treatments to the clinic. [Read more...]

Clinical Applications of Stem Cells – What Could Be Possible?

Stems  cells are promise of the future. There are a number of conditions where stem cells have potential application and tere are many ways in which human stem cells can be used.

One of the primary goals of stem cells is to identify how undifferentiated stem cells become the differentiated cells that form the tissues and organs. Here are the areas where stem cells can help the medicine and human race. [Read more...]

What Are Induced Pluripotent Stem Cells?

Induced pluripotent stem cells (iPSCs) are adult cells that have been genetically reprogrammed to an embryonic stem cell–like state by being forced to express genes and factors important for maintaining the defining properties of embryonic stem cells.

Although these cells meet the defining criteria for pluripotent stem cells, it is not known if iPSCs and embryonic stem cells differ in clinically significant ways.

Mouse iPSCs were first reported in 2006, and human iPSCs were first reported in late 2007.

Mouse iPSCs demonstrate important characteristics of pluripotent stem cells, including expressing stem cell markers, forming tumors containing cells from all three germ layers, and being able to contribute to many different tissues when injected into mouse embryos at a very early stage in development.

Human iPSCs also express stem cell markers and are capable of generating cells characteristic of all three germ layers.

Although additional research is needed, iPSCs are already useful tools for drug development and modeling of diseases, and scientists hope to use them in transplantation medicine. [Read more...]