Regenerative medicine was the term coined by William A. Haseltine in 2000. This  tries to heal the body by stimulation of endogenous cells to repair damaged tissues, or transplantation of cells or engineered tissues to replace diseased or injured.

Tissue injuries are normally repaired by formation of fibrous scar tissue in humans. But a number of tissues in mammals including epithelia, bone marrow, and muscle undergo regeneration to keep tissue integrity after cell loss .

Some lower animals can undertake full organ regeneration.Though not entirely clear, two  mechanisms play roles in regeneration. [Read more...]